Jakafi Tablets 10mg In Pakistan

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PRODUCT DETAILS

Jakafi Tablets 10mg In Pakistan

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Jakafi Tablets 10mg In Pakistan

Jakafi 10mg Tablets contain ruxolitinib, an oral kinase inhibitor used for specific blood and immune-system disorders. The 10mg tablet contains 10mg of ruxolitinib and is a prescription medicine.

Jakafi is prescribed for conditions including myelofibrosis, polycythemia vera, and certain cases of graft-versus-host disease (GVHD). Treatment and dosage must be individualized by a specialist based on the patient's condition, blood counts, and other medical factors.

Key Features

  • Brand: Jakafi
  • Active ingredient: Ruxolitinib
  • Strength: 10mg
  • Oral tablet formulation
  • JAK/kinase inhibitor
  • Prescription medicine
  • Used for selected blood and immune-system conditions
  • Available in multiple strengths

Uses

Jakafi may be prescribed for:

  • Intermediate- or high-risk myelofibrosis in adults
  • Polycythemia vera in adults who have had an inadequate response to or cannot tolerate hydroxyurea
  • Steroid-refractory acute graft-versus-host disease in adults and children aged 12 years and older
  • Chronic graft-versus-host disease after failure of one or two systemic therapies in adults and children aged 12 years and older

The appropriate indication depends on the patient's diagnosis and clinical history.

How It Works

Ruxolitinib works by inhibiting Janus kinase (JAK) enzymes, particularly JAK1 and JAK2. These enzymes participate in signaling pathways involved in blood-cell production and immune responses.

By reducing abnormal JAK signaling, ruxolitinib can help control disease-related symptoms and abnormal blood-cell activity in appropriate patients.

How To Use

Take Jakafi exactly as prescribed by your specialist.

The dosage varies considerably depending on the condition being treated, blood-cell counts, kidney or liver function, and other medicines being used. For example, the current prescribing information lists 10mg twice daily as a starting dose for polycythemia vera and chronic GVHD, but this does not mean 10mg twice daily is appropriate for every patient.

Do not increase, reduce, interrupt, or stop Jakafi without medical supervision.

Regular blood tests are generally required during treatment to monitor blood counts and other safety parameters.

Possible Side Effects

Possible adverse effects can include:

  • Anemia
  • Thrombocytopenia
  • Neutropenia
  • Dizziness
  • Headache
  • Bruising
  • Increased risk of infections
  • Changes in cholesterol levels

Jakafi can cause significant reductions in blood-cell counts and may increase the risk of serious infections.

Contact your healthcare professional promptly if you develop fever, unusual bleeding, severe weakness, or symptoms of infection.

Important Safety Information

Jakafi requires medical monitoring because it can affect platelets, red blood cells, and white blood cells. Your doctor may adjust or temporarily interrupt treatment based on laboratory results.

The prescribing information also warns about infections, non-melanoma skin cancer, cardiovascular events, thrombosis, lipid elevations, and secondary malignancies.

Tell your doctor if you have liver or kidney disease, an active infection, a history of blood clots, or other significant medical conditions.

Inform your healthcare professional about all medicines and supplements you take because certain medicines can interact with ruxolitinib.

Jakafi Tablets 10mg Price In Pakistan

The Jakafi 10mg price in Pakistan varies depending on the pack size, supplier, imported stock, pharmacy, and availability.

The official U.S. product information lists Jakafi 10mg in 28-tablet and 60-tablet bottles.

For the latest Jakafi 10mg price on ClickBazaar.pk, check the current product listing and confirm the exact tablet count, manufacturer, and packaging before ordering.


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